On my current project, we are using subversion and, naturally, TortoiseSVN. One thing that bugged me was that it slows down the build process in Visual Studio to an unacceptable level. I have excluded the root of my c drive like so c:\* but performance is still unacceptable.
So, I found myself killing the TSVCache.exe process before each build. So, my quick fix was to add this command as a pre-build event in my project.
taskkill /T /f /fi "imagename eq TSVNCache.exe"